Temporal and spectral imaging with micro-CT

Temporal and spectral imaging with micro-CT.

PURPOSE Micro-CT is widely used for small animal imaging in preclinical studies of cardiopulmonary disease, but further development is needed to improve spatial resolution, temporal resolution, and material contrast. We present a technique for visualizing the changing distribution of iodine in the cardiac cycle with dual source micro-CT. METHODS The approach entails a retrospectively gated du...

Differential diagnosis of pancreatic cystic masses with the quantitative analysis of spectral CT imaging: Initial results

Background: To retrospectively evaluate whether quantitative information derived from spectral imaging can improve the differential diagnosis of pancreatic cystic masses including pancreatic solid pseudopapillary epithelial neoplasms (SPENs), mucin- producing cysts and pseudocysts. Materials and Methods: From June 2015 to October 2017, 56 patients (22 pseudocysts, 18 mucin-producing cysts and 1...

Correlating Micro-CT Imaging with Quantitative Histology

In-Vivo Imaging of Cartilage Degeneration with Micro-CT

In-vivo evaluation of cartilage degeneration in small animals would be extremely useful for studying the aetiology and treatment of osteoarthritis. Currently, delayed gadolinium enhanced MRI of Cartilage (dGEMRIC) has shown to provide proteoglycan distribution by the diffusion of the contrast agent GdDPTPA in the cartilage, specifically at locations where loss of proteoglycans occurs [1]. A sim...

Digging deeper with CT imaging: slice-by-micro slice...